SDMA: a marker for early kidney damage

Опубліковано

23.04.2024

A marker for early kidney damage (SDMA)

What is SDMA?

SDMA - is an important indicator that helps assess your pet's kidney function. It is a key indicator of function, especially in the early stages of the disease.


SDMA - 

  •  
  • symmetrical dimethylarginine
  • is produced by all nuclear cells at a constant rate
  • is not reabsorbed
  • excreted by the kidneys
  • indirect marker of GFR (glomerular filtration rate)

Detecting kidney problems at an early stage.

  •  
  • SDMA can detect even the slightest changes in kidney function when other blood parameters may remain within normal limits.
  • SDMA detects kidney damage with a loss of function of only 20-40%, while other markers, such as creatinine, increase with a loss of up to 75% of function.
  • SDMA is an extremely valuable marker, because timely diagnosis allows you to start treatment at a stage when you can save your pet's health.

In which animals should SDMA be tested?

  •  
  • Young animals with hereditary kidney disease
  • Animals with congenital kidney disorders
  • Cats over 6 years old
  • Dogs over 10 years old
  • Everyone after acute kidney injury
  • Everyone with kidney disease to establish the stage of CKD (Chronic Kidney Disease)
  • Patients with nephrolithiasis
  • When using nephrotoxic drugs
  • Before anesthesia

How to send an SDMA study to Zoolux?

The ambient temperature should be taken into account when preparing the material
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Sample stability:

  • 4 days at 20-24°C
  • 7-14 days at a temperature of 4 °C
  • Frozen (24 months, down to -80ºС)
  •  

Use serum -500 μL

Thermoses, refrigerants, thermal bags or thermal containers can be used to transport and maintain the temperature of the sample.



Preparation for analysis:

Fasting diet for 8-12 hours (except: other recommendations of the doctor regarding the feeding regimen; puppies, kittens up to 4 months (4 hours), Toy breeds up to 2 months (2 hours))
 

 

Where to send SDMA research:

 

Data for sending the NP: FOP Zayets Olena Oleksandrivna; EDRPOU 3232410446; +380948289838
Kyiv, 39 Dmytrivska St., Zoolux, courier delivery; Payment at the expense of the sender.

You can download the referral here

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